Deletion series in the P1 protein of the Sweet potato mild mottle virus identifies the shortest fully functional RNA silencing suppressor domain

Szabó, Edit Zsuzsanna and Kemény, Lajos and Lakatos, Lóránt: Deletion series in the P1 protein of the Sweet potato mild mottle virus identifies the shortest fully functional RNA silencing suppressor domain. Acta biologica Szegediensis, (58) 2. pp. 163-166. (2014)

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Abstract

RNA silencing is a part of the plant innate immune system that could effectively cope with intruders, like viruses. However, viruses evolved proteins that can suppress RNA silencing thus supporting virus spreading in the host. To counteract RNA silencing, suppressor proteins attack different players of RNA silencing pathway. The P1 protein of the Sweet potato mild mottle virus binds and inactivates small RNA loaded RISC complexes. Using a deletion series in the P1 protein we aimed to identify the possible smallest working version of P1. Our results revealed that the minimal RNA silencing suppressor domain of P1 is as small as 210 amino acids in size.

Item Type: Article
Journal or Publication Title: Acta biologica Szegediensis
Date: 2014
Volume: 58
Number: 2
Page Range: pp. 163-166
ISSN: 1588-385X
Language: angol
Heading title: Article
Uncontrolled Keywords: Dermatológia, Növényélettan
Additional Information: Bibliogr.: 166. p.
Date Deposited: 2016. Oct. 17. 10:37
Last Modified: 2018. May. 25. 10:52
URI: http://acta.bibl.u-szeged.hu/id/eprint/34913

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