Karády Sándor and Browne J. S. L.: Effect of histaminase treatment on histamine and anaphylactic shock in guinea pigs. In: Közlemények a szegedi kir. magy. Ferencz József-Tudományegyetem belgyógyászati klinikájáról 1940-1941. pp. 1-6. (1941)
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Abstract
In guinea pigs, the intravenous injection of histaminase 15 minutes before the intraabdominal injection of 4 mgm. of histamine prevented in most instances the symptoms of histamineshock. Of 10 control animals, all showed marked symptoms within 5 to 7 minutes and 7 animals died shortly after. Of the 20 animals pretreated with histaminase, 6 showed slight symptoms after 15 minutes, which disappeared in a few minutes in all but 2 animais that died 55 minutes after the injection of the histamine. 2. Histaminase given intravenously 15 minutes before the administration of egg-white intruabdominally to previously sensitized guinea pigs prevented an anaphylactic shock completely in 15 out of 20 animals. The other 5 guinea, pigs showed only very slight symptoms beginning 20 minutes after the injection of egg-white and lasting for a few minutes. Of the 10 control animals all showed severe anaphylactic shock developing within 5 to 10 minutes and 4 animals died 10 to 14 minutes after the injection of the egg-white.
| Item Type: | Book Section |
|---|---|
| Journal or Publication Title: | Közlemények a szegedi kir. magy. Ferencz József-Tudományegyetem belgyógyászati klinikájáról 1940-1941 |
| Date: | 1941 |
| Page Range: | pp. 1-6 |
| Series Name: | Közlemények a szegedi kir. magy. Ferencz József-Tudományegyetem belgyógyászati klinikájáról |
| Language: | English |
| Related URLs: | http://acta.bibl.u-szeged.hu/53826/ |
| Uncontrolled Keywords: | Állatkísérletek, Tengeri malac, Allergia - hisztamin, Anafilaxia, Immunológia |
| Additional Information: | Bibliogr.: 6. p. ; Összfoglalás angol nyelven |
| Subjects: | 03. Medical and health sciences 03. Medical and health sciences > 03.02. Clinical medicine |
| Date Deposited: | 2018. Jun. 27. 05:19 |
| Last Modified: | 2022. Jan. 07. 09:19 |
| URI: | http://acta.bibl.u-szeged.hu/id/eprint/54212 |
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