Environmental monitoring of glyphosate and assessment of its combined cytotoxicity with adjuvants

Ottucsák Marianna and Klátyik Szandra and Gyurcsó Gergő and Mörtl Mária and Darvas Béla and Székács András: Environmental monitoring of glyphosate and assessment of its combined cytotoxicity with adjuvants.

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Abstract

Pesticide toxicology currently focuses mainly on two areas: long-term effects of given compounds and cocktail effects of chemicals, including combined effects of pesticide active ingredients with their adjuvants, as seen in the case of glyphosate-based herbicides. In this study surface water pollution in an agricultural region of Hungary by glyphosate was determined by ELISA method, and cytotoxic effects on HEK293 and NE-4C cells by glyphosate, its formulated herbicide (ROUNDUP® ) and adjuvant (polyethoxylated tallowamine, POEA) were compared. ROUNDUP and POEA were found to be equitoxic at short exposures (LC50: 10-15 ng/ml in 6 hrs), while glyphosate occurred to be of 500-750-fold less toxicity.

Item Type: Conference or Workshop Item
Journal or Publication Title: Proceedings of the International Symposium on Analytical and Environmental Problems
Date: 2015
Volume: 21
ISBN: 978-963-306-411-5
Page Range: pp. 64-67
Event Title: International Symposium on Analytical and Environmental Problems (21.) (2015) (Szeged)
Related URLs: http://acta.bibl.u-szeged.hu/55892/
Uncontrolled Keywords: Kémia, Biokémia, Peszticid, Toxikológia
Additional Information: Bibliogr.: 67. p. ; összefoglalás angol nyelven
Date Deposited: 2018. Dec. 05. 10:50
Last Modified: 2022. Aug. 08. 15:47
URI: http://acta.bibl.u-szeged.hu/id/eprint/55929

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