Rabbits in vivo experiments and hematological evaluation after iron toxicity

Ahmadi Mirela and Dronca Dorel and Milovanov Cornelia and Boldura Oana-Maria and Hutu Ioan and Mircu Calin and Tulcan Camelia: Rabbits in vivo experiments and hematological evaluation after iron toxicity.

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Abstract

Iron is essential elements for human, animals and plant organism. The depletion of organism in iron leads to modification in the concentration of hemoglobin which is responsible for oxygen transportation. Also, overload of iron represents a possible intoxication that can affect negatively the liver tissue and then all cells. Our experiments was conducted on two groups (control and experimental) of rabbits – German Lop Eared Rabbits breed, and we administrated ferrous gluconate (10mg/kg body weight) to the experimental group, two times. Also, during the experiment the rabbits had a special diet with plants from garden administrated fresh. The plants have very good antioxidant properties, and can prevent the iron intoxication and also participate intense to detoxification of the liver after iron overload. Hematological analysis were preformed for red blood cells, hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, red cell distribution width, platelet and leukocyte evaluation. The results demonstrated a very good protective action of the diet plants, meaning that the hematological parameters were not out of normal range after iron overload.

Item Type: Conference or Workshop Item
Journal or Publication Title: Proceedings of the International Symposium on Analytical and Environmental Problems
Date: 2015
Volume: 21
ISBN: 978-963-306-411-5
Page Range: pp. 87-91
Event Title: International Symposium on Analytical and Environmental Problems (21.) (2015) (Szeged)
Related URLs: http://acta.bibl.u-szeged.hu/55892/
Uncontrolled Keywords: Vas, Kísérleti állatok, Nyúl, Hematológia
Additional Information: Bibliogr.: 91. p. ; ill. ; összefoglalás angol nyelven
Date Deposited: 2018. Dec. 05. 12:52
Last Modified: 2022. Aug. 08. 15:47
URI: http://acta.bibl.u-szeged.hu/id/eprint/55934

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