Laboratory challenges of detecting synthetic cannabinoids in urine samples - a new sample preparation method

Barna, Boglárka and Körmöczi, Tímea and Sija, Éva and Berkecz, Róbert: Laboratory challenges of detecting synthetic cannabinoids in urine samples - a new sample preparation method. Proceedings of the International Symposium on Analytical and Environmental Problems, (24). pp. 59-63. (2018)

[img] Cikk, tanulmány, mű
proceedings_of_isaep_2018_059-063.pdf

Download (731kB)

Abstract

Synthetic cannabinoids (SCs) put the spotlight on the designer drugs’ market due to their dangerous – in some cases lethal – biological effects and easy accessibility. They are more potent than the well-known Δ⁹-tetrahydrocannabinol (THC) thanks to their special pharmacodynamic properties. The number of novel SCs on the market and of their users is growing which urges the forensic laboratories to use precise SCs detection methods routinely. Our aim was to develop a new sample preparation method for the newest 24 SCs analysis in urine samples achieving high recovery of SCs. Ethyl acetate was used instead of the traditional acetonitrile, and the targeted analysis of SCs was performed by use of liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-MS/MS) method. The related matrix effect and process efficiency of sample preparation method were taken in consideration as well in our study.

Item Type: Article
Journal or Publication Title: Proceedings of the International Symposium on Analytical and Environmental Problems
Date: 2018
Volume: 24
Page Range: pp. 59-63
ISBN: 978-963-306-623-2
Uncontrolled Keywords: Kémia, Laboratóriumi technika - kémia
Additional Information: Bibliogr.: 63. p. ; összefoglalás angol nyelven
Date Deposited: 2019. Jan. 04. 06:57
Last Modified: 2019. Jan. 04. 06:57
URI: http://acta.bibl.u-szeged.hu/id/eprint/56279

Actions (login required)

View Item View Item