Chronobiological changes induced by the gallium complex C(24) in some hematological parameters in rats

Gârban, Zeno and Ioniţă, Hortensia and Gârban, Gabriela and Baltă, Cornel and Ahmadi-Vincu, Mirela and Muselin, Florin and Lungu, Camelia and Acatincăi, St. and Újhelyi, Róbert and Simiz, Eliza and Boldura, Oana-Maria: Chronobiological changes induced by the gallium complex C(24) in some hematological parameters in rats. Proceedings of the International Symposium on Analytical and Environmental Problems, (24). pp. 230-234. (2018)

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Abstract

In the present research the authors proposed to monitor possible chronobiological changes in some hematological parameters (erythrocytes, leukocytes and thrombocytes) of Wistar strain rats induced by the novel gallium complex - C(24). For this purpose a morning (m) and an evening (e) animal series were designed, each including a control (Cp) and an experimental (E) group. Animals of the control groups (Cp-m, Cp-e) were injected intraperitoneally with polyethylene glycol and those from the experimental groups (E-m, E-e) with the novel gallium complex in the morning and in the evening. At 48 hours after the administration of substances the animals were anesthetized and blood samples were collected for biochemical and hematological analysis. Erythrocytes, leukocytes and thrombocytes parameters were determined. The resulted values showed an increase in most of erythrocytes parameters in E-m group and a slight decrease of all parameters in E-e group. As to leukocytes parameters an increase of most values both in E-m and E-e groups was recorded. Platelets parameters indicated decrease both in E-m and E-e groups, being more evident in case of platelets number.

Item Type: Article
Journal or Publication Title: Proceedings of the International Symposium on Analytical and Environmental Problems
Date: 2018
Volume: 24
Page Range: pp. 230-234
ISBN: 978-963-306-623-2
Uncontrolled Keywords: Kronobiológia, Biokémia, Hematológia, Kísérleti állatok
Additional Information: Bibliogr.: p. 233-234. ; összefoglalás angol nyelven
Date Deposited: 2019. Jan. 07. 10:22
Last Modified: 2019. Jan. 07. 10:22
URI: http://acta.bibl.u-szeged.hu/id/eprint/56335

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