Determination of valine and leucine isomers in peptaibols

Endre Gábor and Marik Tamás and Kredics László and Varga Mónika and Vágvölgyi Csaba and Szekeres András: Determination of valine and leucine isomers in peptaibols.

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Abstract

Peptaibols are oligomers, containing non-proteogenic amino acids. Some of them are considered as antifungal and antibiotic agents, therefore the elucidation of their structure is important. There have been a lot of efforts determining their amino acid sequences via mass spectrometry, but isobaric components cannot be determined using this technique. In this work, a HPLC method development was carried out for the determination of leucine, isoleucine, valine and isovaline in one chromatographic run. Furthermore, a chiral separation of the optical isomers of these compounds has been also solved.

Item Type: Conference or Workshop Item
Journal or Publication Title: Proceedings of the International Symposium on Analytical and Environmental Problems
Date: 2018
Volume: 24
ISBN: 978-963-306-623-2
Page Range: pp. 283-285
Event Title: International Symposium on Analytical and Environmental Problems (24.) (2018) (Szeged)
Related URLs: http://acta.bibl.u-szeged.hu/55895/
Uncontrolled Keywords: Gyógyszerkémia, Mikrobiológia
Additional Information: Bibliogr.: 285. p. ; összefoglalás angol nyelven
Date Deposited: 2019. Jan. 07. 13:22
Last Modified: 2022. Aug. 08. 15:50
URI: http://acta.bibl.u-szeged.hu/id/eprint/56350

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