Endre, Gábor and Marik, Tamás and Kredics, László and Varga, Mónika and Vágvölgyi, Csaba and Szekeres, András: Determination of valine and leucine isomers in peptaibols. In: Proceedings of the International Symposium on Analytical and Environmental Problems, (24). pp. 283-285. (2018)
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Abstract
Peptaibols are oligomers, containing non-proteogenic amino acids. Some of them are considered as antifungal and antibiotic agents, therefore the elucidation of their structure is important. There have been a lot of efforts determining their amino acid sequences via mass spectrometry, but isobaric components cannot be determined using this technique. In this work, a HPLC method development was carried out for the determination of leucine, isoleucine, valine and isovaline in one chromatographic run. Furthermore, a chiral separation of the optical isomers of these compounds has been also solved.
| Item Type: | Article |
|---|---|
| Journal or Publication Title: | Proceedings of the International Symposium on Analytical and Environmental Problems |
| Date: | 2018 |
| Volume: | 24 |
| ISBN: | 978-963-306-623-2 |
| Page Range: | pp. 283-285 |
| Uncontrolled Keywords: | Gyógyszerkémia, Mikrobiológia |
| Additional Information: | Bibliogr.: 285. p. ; összefoglalás angol nyelven |
| Date Deposited: | 2019. Jan. 07. 13:22 |
| Last Modified: | 2019. Jan. 07. 13:22 |
| URI: | http://acta.bibl.u-szeged.hu/id/eprint/56350 |
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