Microwave-assisted Pd-catalyzed C-P or C-C cross couplings on 13α-estrane core

Jójárt, Rebeka and Trungel-Nagy, Péter and Pécsy, Szabolcs and Szlávik, Márton and Horváth, Gergely and Ágoston, Henrietta and Mernyák, Erzsébet: Microwave-assisted Pd-catalyzed C-P or C-C cross couplings on 13α-estrane core. Proceedings of the International Symposium on Analytical and Environmental Problems, (24). pp. 296-298. (2018)

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Abstract

Novel 2- or 4-substituted 13α-estrone derivatives were synthesized via Hirao or Suzuki reaction. Transformations of 2- and/or 4-halogenated derivatives of 13α-estrone and its 3- benzyl or -methyl ether were carried out in a microwave (MW) reactor. Facile and efficient CC or C-P coupling procedures were established using Pd or Ni catalysts. The newly synthesized compounds might have promising antitumoral properties.

Item Type: Article
Journal or Publication Title: Proceedings of the International Symposium on Analytical and Environmental Problems
Date: 2018
Volume: 24
Page Range: pp. 296-298
ISBN: 978-963-306-623-2
Uncontrolled Keywords: Szerves kémia
Additional Information: Bibliogr.: 298. p. ; összefoglalás angol nyelven
Date Deposited: 2019. Jan. 07. 13:39
Last Modified: 2019. Jan. 07. 13:39
URI: http://acta.bibl.u-szeged.hu/id/eprint/56354

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