Shahmohammadi Sayeh and Forró Enikő and Fülöp Ferenc: Synthesis of new fluorine-containing β-amino acid enantiomers through lipase catalyzed hydrolysis.
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Abstract
An efficient and novel enzymatic method was developed for the synthesis of β-aryl-fluorinecontaining β-amino acid enantiomers through lipase PS IM (Burkholderia cepasia) catalyzed hydrolysis in i-Pr2O at 45 °C in the presence of Et3N. In order to follow the enzymatic reactions, an adequate analytical method was devised for the enantioseparation of racemic βamino esters and β-amino acids.
| Item Type: | Conference or Workshop Item |
|---|---|
| Journal or Publication Title: | Proceedings of the International Symposium on Analytical and Environmental Problems |
| Date: | 2019 |
| ISBN: | 978-963-306-702-4 |
| Page Range: | pp. 392-393 |
| Event Title: | International Symposium on Analytical and Environmental Problems (25.) (2019) (Szeged) |
| Related URLs: | http://acta.bibl.u-szeged.hu/64947/ |
| Uncontrolled Keywords: | Gyógyszerkémia |
| Additional Information: | Bibliogr.: 393. p. ; összefoglalás angol nyelven |
| Date Deposited: | 2020. Mar. 23. 08:26 |
| Last Modified: | 2022. Aug. 08. 15:37 |
| URI: | http://acta.bibl.u-szeged.hu/id/eprint/64888 |
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