New way to green biological assays fluorescent steroids replace radioisotopes

Szabó Vivien and Orosz Boglárka Anna and Rigó Réka and Özvegy-Laczka Csilla and Mernyák Erzsébet: New way to green biological assays fluorescent steroids replace radioisotopes.

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Abstract

Novel BODIPY–estrone and BODIPY–estradiol conjugates have been synthesized via Cu(I)- catalyzed azide-alkyne click (CuAAC) and/or Sonogashira reactions by selecting position C3-O for labeling. The steroidal azides and/or bromides were reacted with BODIPY-based fluorescent dye bearing alkyne function. The new fluorescent estrone conjugates might replace radiolabeled compounds in certain biochemical assays.

Item Type: Conference or Workshop Item
Journal or Publication Title: Proceedings of the International Symposium on Analytical and Environmental Problems
Date: 2019
ISBN: 978-963-306-702-4
Page Range: pp. 437-438
Event Title: International Symposium on Analytical and Environmental Problems (25.) (2019) (Szeged)
Related URLs: http://acta.bibl.u-szeged.hu/64947/
Uncontrolled Keywords: Szerves kémia
Additional Information: Bibliogr.: 438. p. ; összefoglalás angol nyelven
Date Deposited: 2020. Mar. 23. 11:33
Last Modified: 2022. Aug. 08. 15:37
URI: http://acta.bibl.u-szeged.hu/id/eprint/64901

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