Jójárt Rebeka and Kóczán Lili and Fajka Lilla and Bartha Sándor and Minorics Renáta and Zupkó István and Mernyák Erzsébet: Microwave-assisted phospha-Michael addition reactions on 13αestrane core.
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Abstract
Novel 16-modified 13 α-estrone derivatives were synthesized via phospha-Michael addition reactions. Transformations of steroidal α,β-unsaturated ketons were carried out under different conditions in a microwave (MW) reactor. The antiproliferative activities of the newly synthesized compounds against a range of human adherent cancer cell lines (SCC-131, SCC154, Hela, SiHa, C33A, A2780, MCF-7, MDA-MB-231, T47D) were investigated by means of MTT assays. Certain potent derivatives were identified.
| Item Type: | Conference or Workshop Item |
|---|---|
| Journal or Publication Title: | Proceedings of the International Symposium on Analytical and Environmental Problems |
| Date: | 2020 |
| Volume: | 26 |
| ISBN: | 978-963-306-771-0 |
| Page Range: | pp. 177-178 |
| Language: | English |
| Event Title: | International Symposium on Analytical and Environmental Problems (26.) (2020) (Szeged) |
| Related URLs: | http://acta.bibl.u-szeged.hu/73792/ |
| Uncontrolled Keywords: | Kémia |
| Additional Information: | Bibliogr.: 178. p. ; összefoglalás angol nyelven |
| Subjects: | 01. Natural sciences 01. Natural sciences > 01.04. Chemical sciences |
| Date Deposited: | 2021. Nov. 17. 12:39 |
| Last Modified: | 2022. Aug. 08. 15:39 |
| URI: | http://acta.bibl.u-szeged.hu/id/eprint/73989 |
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