Analytical investigation techniques in the service of liposome development

Németh Zsófia and Dobó Dorina Gabriella and Pallagi Edina and Csóka Ildikó: Analytical investigation techniques in the service of liposome development.

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Abstract

The quality of the liposome formulations differs based on the features of the compositions. Several investigation methods help with their results to make the right decision to achieve an optimised preparation. During these sets of experiments to prepare liposomes via the thin-film hydration technique, dynamic light scattering (DLS) and zeta potential measurements, thermogravimetric analysis (TGA), differential scanning calorimetry (DSC) investigations, and Fourier-transformed infrared (FT-IR) studies were used to select the more optimal compositions. The formulations differed in the phospholipid-cholesterol ratio, the type of the applied PEGylated phospholipid, the quality of the solvent, the hydration media and the cryoprotectant.

Item Type: Conference or Workshop Item
Journal or Publication Title: Proceedings of the International Symposium on Analytical and Environmental Problems
Date: 2020
Volume: 26
ISBN: 978-963-306-771-0
Page Range: pp. 271-272
Language: English
Event Title: International Symposium on Analytical and Environmental Problems (26.) (2020) (Szeged)
Related URLs: http://acta.bibl.u-szeged.hu/73792/
Uncontrolled Keywords: Analitikai kémia
Additional Information: Bibliogr.: 272. p. ; összefoglalás angol nyelven
Subjects: 01. Natural sciences
01. Natural sciences > 01.04. Chemical sciences
Date Deposited: 2021. Nov. 18. 08:42
Last Modified: 2022. Aug. 08. 15:39
URI: http://acta.bibl.u-szeged.hu/id/eprint/74011

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