Kmetykó Noémi and Wilhelm Imola and Ilisz István and Berkecz Róbert: Transport study of kynurenic acid and its newest derivatives through and in vitro model of the blood-brain barrier using targeted UHPLC-MS\MS.
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Abstract
We have developed a targeted UHPLC-ESI–MS/MS method for the quantification of kynurenic acid (KYNA) and its derivatives from biological samples. The samples were gained from in vitro permeability assay. We have found that the transportation of the derivatives through the blood-brain barrier is better than KYNA.
| Item Type: | Conference or Workshop Item |
|---|---|
| Journal or Publication Title: | Proceedings of the International Symposium on Analytical and Environmental Problems |
| Date: | 2020 |
| Volume: | 26 |
| ISBN: | 978-963-306-771-0 |
| Page Range: | pp. 404-405 |
| Language: | English |
| Event Title: | International Symposium on Analytical and Environmental Problems (26.) (2020) (Szeged) |
| Related URLs: | http://acta.bibl.u-szeged.hu/73792/ |
| Uncontrolled Keywords: | Biofizika, Fizikai kémia |
| Additional Information: | Összefoglalás angol nyelven |
| Subjects: | 01. Natural sciences 01. Natural sciences > 01.04. Chemical sciences |
| Date Deposited: | 2021. Nov. 18. 16:03 |
| Last Modified: | 2022. Aug. 08. 15:39 |
| URI: | http://acta.bibl.u-szeged.hu/id/eprint/74049 |
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