2-OXO-1,2,3,4-tetrahydropyrimidine-azo-pyridone dye : a potential application as new green-emitting fluorescent probe

Tadić Julijana and Janković Nenad and Lađarević Jelena and Porobić Slavica and Kojić Marija and Marinović-Cincović Milena and Mijn Dušan: 2-OXO-1,2,3,4-tetrahydropyrimidine-azo-pyridone dye : a potential application as new green-emitting fluorescent probe.

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Abstract

Molecular imaging is a relatively new research field, which has demonstrated great potential, especially in clinical oncology – from drug development to cancer early detection. The key of fluorescence imaging is the construction of fluorescent probe which is composed of two parts, the recognition groups to recognize cancer cells, and fluorophores to signal the recognition events. In this research, the structure of new fluorescent azo dye based on 2-oxo-1,2,3,4-tetrahydropyrimidin and 2-pyridone moieties has been reported. The absorption and emission properties of the investigated azo dye have been studied using UV-Vis and fluorescence spectroscopy. The obtained results suggest that studied dye meets the requirements for new green-emitting fluorescent probe, suitable for further application in biomedical researches.

Item Type: Conference or Workshop Item
Journal or Publication Title: Proceedings of the International Symposium on Analytical and Environmental Problems
Date: 2021
Volume: 27
ISBN: 978-963-306-835-9
Page Range: pp. 324-326
Language: English
Publisher: University of Szeged
Place of Publication: Szeged
Event Title: International Symposium on Analytical and Environmental Problems (27.) (2021) (Szeged)
Related URLs: http://acta.bibl.u-szeged.hu/75798/
Uncontrolled Keywords: Kémia
Additional Information: Bibliogr.: 326. p. ; ill. ; összefoglalás angol nyelven
Subjects: 01. Natural sciences
01. Natural sciences > 01.04. Chemical sciences
Date Deposited: 2022. Jun. 01. 09:40
Last Modified: 2022. Aug. 08. 15:40
URI: http://acta.bibl.u-szeged.hu/id/eprint/75997

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