Experimental study of the interaction of one local anesthetic with a cellulose type support

Simu Georgeta-Maria and Muntean Simona Gabriela and Grad Maria: Experimental study of the interaction of one local anesthetic with a cellulose type support.

Cikk, tanulmány, mű proceedings_of_isaep_2011_355-358.pdf Download (1MB)

Abstract

The extent of the adsorption of a local anesthetic (Bupivacaine) on a pharmaceutical adsorbent, namely microcrystalline cellulose (MCC) suspended in aqueous solution was investigated spectrophotometrically at three different temperatures. The equilibrium adsorption contact times were determined for all the temperatures and were found around 90 minutes. Adsorption isotherms have been analyzed by the Freundlich and Langmuir models. The obtained results indicated that the Freundlich isotherms presented the highest correlation coefficients, and thus they describe better the adsorption of the studied drug on MCC.

Item Type:	Conference or Workshop Item
Journal or Publication Title:	Proceedings of the International Symposium on Analytical and Environmental Problems
Date:	2012
Volume:	17
ISBN:	978-963-315-066-5
Page Range:	pp. 355-358
Language:	English
Publisher:	SZAB
Place of Publication:	Szeged
Event Title:	International Symposium on Analytical and Environmental Problems (17.) (2011) (Szeged)
Event Type:	Conference
Event Location:	Szeged
Event Dates:	2011. szeptember 19.
Related URLs:	http://acta.bibl.u-szeged.hu/76381/
Uncontrolled Keywords:	Gyógyszerkémia
Additional Information:	Bibliogr.: 358. p. ; összefoglalás angol nyelven
Subjects:	01. Natural sciences 01. Natural sciences > 01.04. Chemical sciences 03. Medical and health sciences 03. Medical and health sciences > 03.01. Basic medicine
Date Deposited:	2022. Aug. 10. 14:24
Last Modified:	2022. Aug. 22. 10:23
URI:	http://acta.bibl.u-szeged.hu/id/eprint/76462

Actions (login required)

View Item