Novel platinum complexes with schiff bases and α-Dioximes, their physico-chemical and biological study

Várhelyi Csaba and Szalay Roland and Pokol György and Madarász János and Huszthy Péter and Simon-Várhelyi Melinda and Tötös Róbert and Mereu Raluca-Anca and Papp Judit and Mihály Judith: Novel platinum complexes with schiff bases and α-Dioximes, their physico-chemical and biological study.

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Abstract

In our research project we prepared the following platinum(II) complexes with Schiff bases and -dioximes, such as [Pt(ketone)2A(L2)], (ketone: 2-heptanone, 2-octanone, 3-octanone; A: hydrazine, phenylhydrazine, o-phenylene-diamine; L: 1-naphthylamine, 2-aminopyrimidine, 2-methylimidazole, 2-amino-4-methylpyridine) and [Pt(DioxH)2L2], (DioxH2: methyl-phenyl-dioxime, butyl-methyl-dioxime; L: 1-naphthylamine, 2-methylimidazole, 2-amino-4-methylpyridine, lepidine, 2-methylpyridine, m-toluidine, dicyclohexylamine, 4-isopropylamine, cyclohexylamine), by the reaction of PtCl2 in suitable solvent. After a short bibliographical survey, involving the classification and evolution of platinum complexes with possible applications, we analyzed their physico-chemical properties using FTIR, Raman, NMR, UV-VIS spectroscopy, powder X-ray diffraction (XRD), mass spectrometry, thermal analysis (TG, DTG, DTA) and SEM. We also studied the antibacterial effect of complexes on different strains of bacteria. This class of compounds has relevance in biochemistry, some of them are antibacterial agents and potential anti-tumor drugs.

Item Type: Conference or Workshop Item
Journal or Publication Title: Proceedings of the International Symposium on Analytical and Environmental Problems
Date: 2023
Volume: 29
ISBN: 978-963-306-963-9
Page Range: pp. 50-55
Language: English
Publisher: University of Szeged
Place of Publication: Szeged
Event Title: 29th International Symposium on Analytical and Environmental Problems
Event Type: Conference
Event Location: Szeged
Event Dates: 2023. november 13-14.
Related URLs: https://acta.bibl.u-szeged.hu/82256/
Uncontrolled Keywords: Környezetkémia
Additional Information: Bibliogr.: p. 54-55. ; összefoglalás angol nyelven
Subjects: 01. Natural sciences
01. Natural sciences > 01.04. Chemical sciences
Date Deposited: 2023. Nov. 21. 15:05
Last Modified: 2023. Nov. 21. 15:05
URI: http://acta.bibl.u-szeged.hu/id/eprint/82362

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