Spasojević Jelena and Vukoje Ivana and Nikolić Nikolina and Milošević Milica and Ranković Dragana and Radosavljević Aleksandra: Kinetic aspects of silver ions release from Ag-poly (N-isopropylacrylamide/itaconic acid) hydrogel nanocomposites.
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Abstract
In recent years, drug delivery systems have been one of the most investigated solutions for safer and more efficient therapy. Among many investigated materials, hydrogels with incorporated drugs and/or active substances can be produced in different ways to meet the criteria of biocompatibility, non-toxicity, continuous drug delivery, etc. In our previous work, the AgP(NiPAAm/IA) hydrogel nanocomposites were produced by radiolytic method, which enabled the synthesis and sterilization of materials in one technological step. Because of silver ions release, these hydrogel nanocomposites showed good antibacterial potential against both grampositive and gram-negative bacteria. In this study, we go a step forward and investigate the silver release mechanism by fitting experimentally obtained data with several commonly used kinetics models of drug release.
| Item Type: | Conference or Workshop Item |
|---|---|
| Journal or Publication Title: | Proceedings of the International Symposium on Analytical and Environmental Problems |
| Date: | 2023 |
| Volume: | 29 |
| ISBN: | 978-963-306-963-9 |
| Page Range: | pp. 303-307 |
| Language: | English |
| Publisher: | University of Szeged |
| Place of Publication: | Szeged |
| Event Title: | 29th International Symposium on Analytical and Environmental Problems |
| Event Type: | Conference |
| Event Location: | Szeged |
| Event Dates: | 2023. november 13-14. |
| Related URLs: | https://acta.bibl.u-szeged.hu/82256/ |
| Uncontrolled Keywords: | Gyógyszerkémia |
| Additional Information: | Bibliogr.: 307. p. ; ill. ; összefoglalás angol nyelven |
| Subjects: | 01. Natural sciences 01. Natural sciences > 01.04. Chemical sciences 03. Medical and health sciences 03. Medical and health sciences > 03.01. Basic medicine |
| Date Deposited: | 2023. Nov. 27. 13:18 |
| Last Modified: | 2023. Nov. 27. 13:18 |
| URI: | http://acta.bibl.u-szeged.hu/id/eprint/82461 |
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