Early stage lymph node positive cervical cancer treated with laterally extended parametrectomy (LEP)

Ungár László and Tarnai László: Early stage lymph node positive cervical cancer treated with laterally extended parametrectomy (LEP). In: Ünnepi e-könyv : Herczeg János professzor 70. születésnapjára. pp. 216-228. (2012)

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Abstract

Introduction: In 2003, we published our preliminary experience with the use of an operative technique (laterally extended parametrectomy, the LEP procedure) without adjuvant therapy, in the treatment of 29 stage IB, cervical cancer patients with pelvic lymph node metastases. In our present paper, by an extended recruiting period, with a completed 5 years follow up, we studied the outcome of LEP operations, used with the same indications. Methods: In 70 out of 106 LEP-Wertheim operated patients, no adjuvant treatment was used. In 36 patients, where histology suggested tumor spread beyond the threshold of our surgery, adjuvant chemo-radiotherapy was advised. 5 years follow up was completed (without lost for follow up) for the whole cohort of patients. Results: In 70 patients treated by LEP procedure alone, the overall 5-years survival was 91.4%. For those 36 patients, who were excluded due to disease spread above study criteria, 5 years survival was 44%. Complications in 10% of cases necessitated a second operation. Apart from transient hyper continence and one case of permanent incontinence, no severe quality of life consequence of the operation was observed. Conclusions: Our results suggest that in 2/3rd of pelvic lymph node positive, stage IB cervical cancer cases surgery alone could provide equal or better survival ( without the toxicity of chemoradiotherapy), than any kind of multimodality treatment alternatives. LEP procedure should be considered a treatment option for stage IB cervical cancer patients with pelvic lymph node metastases.

Item Type:	Book Section
Heading title:	Orvosi tanulmányok
Journal or Publication Title:	Ünnepi e-könyv : Herczeg János professzor 70. születésnapjára
Date:	2012
ISBN:	978 963 306 154 1
Page Range:	pp. 216-228
Language:	English
Publisher:	Szegedi Tudományegyetem Állam- és Jogtudományi Kar
Place of Publication:	Szeged
Related URLs:	https://acta.bibl.u-szeged.hu/84656/
Uncontrolled Keywords:	Méhnyakrák - diagnosztika, Méhnyakrák - kezelés, Nőgyógyászat - terápia
Additional Information:	Bibliogr.: p. 225-228. ; összefoglalás angol nyelven
Subjects:	03. Medical and health sciences 03. Medical and health sciences > 03.02. Clinical medicine
Date Deposited:	2024. Apr. 09. 12:06
Last Modified:	2024. Apr. 09. 12:06
URI:	http://acta.bibl.u-szeged.hu/id/eprint/84683

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