Identification and characterization of sialylated glycolipids in TLR2D knockout gene

Ica Raluca and Sarbu Mirela and Mlinac-Jerković Kristina and Kalanj-Bognar Svjetlana and Biricioiu Roxana and Zamfir Alina D.: Identification and characterization of sialylated glycolipids in TLR2D knockout gene.

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Abstract

Gangliosides, complex glycosphingolipids essential for the central nervous system, play crucial roles in cellular processes such as cell adhesion, signal transduction, and cell-to-cell communication. Alterations in ganglioside composition are associated with various neurological disorders, underscoring the importance of studying these molecules for a better understanding of neural function and pathology. This study characterized the ganglioside profiles in mouse brain tissues from four distinct groups: wild-type females (WF), knockout females (KF) with the TLR2D gene inhibited, wild-type males (WM), and knockout males (KM).

Item Type: Conference or Workshop Item
Journal or Publication Title: Proceedings of the International Symposium on Analytical and Environmental Problems
Date: 2024
Volume: 30
ISBN: 978-963-688-009-5
Page Range: pp. 98-99
Language: English
Publisher: University of Szeged
Place of Publication: Szeged
Event Title: 30th International Symposium on Analytical and Environmental Problems
Event Type: Conference
Event Location: Szeged
Event Dates: 2024. október 7-8.
Related URLs: https://acta.bibl.u-szeged.hu/85607/
Uncontrolled Keywords: Molekuláris biológia, Immunológia - kutatás, Lipidomika, Genetika
Additional Information: Bibliogr.: 99. p. ; összefoglalás angol nyelven
Subjects: 01. Natural sciences
01. Natural sciences > 01.04. Chemical sciences
03. Medical and health sciences
03. Medical and health sciences > 03.01. Basic medicine
Date Deposited: 2024. Nov. 21. 10:35
Last Modified: 2024. Nov. 21. 10:35
URI: http://acta.bibl.u-szeged.hu/id/eprint/85678

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