relation: http://acta.bibl.u-szeged.hu/64770/ title: Novel nickel complexes with schiff bases and α-glyoximes, synthesis and physical-chemical study creator: Várhelyi Csaba creator: Szalay Roland creator: Pokol György creator: Goga Firuţa creator: Huszthy Péter creator: Várhelyi Melinda creator: Golban Ligia Mirabela creator: Bogdan Alexandra creator: Demeter Lóránd description: Nickel complexes, especially with Schiff bases gain potential interest in various areas such as catalysis, luminescent probes in analytical chemistry, dye and polymer industry, food industry, magneto-structural chemistry, agrochemistry, biological fields and several miscellaneous applications. There are numerous reports on the biological activities of Schiff base ligands and their metal complexes, including their use for DNA cleavage, enzyme modeling, and as antimicrobial, antifungal and antitumor agents [1]. In our research, new nickel complexes were synthesized with α-glyoximes, such as [Ni(Me-propyl-GlyoxH)2(imidazole)2], [Ni(Me-pentyl-GlyoxH)2(diisopropyl-amine)2], [Ni((4-benzyl-2-hydroxy-phenyl)-Me-GlyoxH)2], where GlyoxH = mono deprotonated glyoxime, and with Schiff bases, such as [Ni(3-heptanone)2A], [Ni(propiophenone)2A], A = ethylenediamine (en), 1,2-, 1,3-propylenediamine (1,2-pn, 1,3-pn), o-phenylene-diamine (o-fen). The Schiff bases were obtained with a simple condensation reaction between 3- heptanone or propiophenone and the corresponding diamines. The molecular structure of our products was investigated by IR, UV–VIS spectroscopy, mass spectrometry (MS), thermoanalytical measurements (TG-DTG-DTA), and powder XRD. The biological activity was studied for a few bacteria, however, these complexes have shown no antibacterial activity so far. date: 2019 type: Konferencia vagy workshop anyag type: NonPeerReviewed format: part language: hu identifier: http://acta.bibl.u-szeged.hu/64770/1/proceedings_of_isaep_2019_032-036.pdf identifier: Várhelyi Csaba; Szalay Roland; Pokol György; Goga Firuţa; Huszthy Péter; Várhelyi Melinda; Golban Ligia Mirabela; Bogdan Alexandra; Demeter Lóránd: Novel nickel complexes with schiff bases and α-glyoximes, synthesis and physical-chemical study.