Experimental study of the ibuprofene’s interaction with some natural supports

Simu Georgeta-Maria; Grad Maria; Fessi Sabrine: Experimental study of the ibuprofene’s interaction with some natural supports.

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The interaction of ibuprofene with two natural solid supports (orange peel and cotton fibre) was studied at three different temperatures (25, 35 and 45 oC) aiming to establish the best theoretical adsorption model and the corresponding thermodynamic parameters (enthalpy and entropy) of the process. For the investigated systems, the time necessary for attaining the adsorption equilibrium was estimated through a series of preliminary experiments, which indicated periods of time ranging from 195 to 380 minutes. Further, the experimental data resulted from the adsorption process was fitted to the Freundlich and Langmuir classical adsorption models, but also to the Sips and Jossens isotherm models, which were not tested yet in the case of the present studied systems. The obtained results showed that for both investigated systems it was the Sips model which described better the interaction of the model drug with the investigated solid supports.

Mű típusa: Konferencia vagy workshop anyag
Befoglaló folyóirat/kiadvány címe: Proceedings of the International Symposium on Analytical and Environmental Problems
Dátum: 2015
Kötet: 21
ISBN: 978-963-306-411-5
Oldalak: pp. 282-286
Konferencia neve: International Symposium on Analytical and Environmental Problems (21.) (2015) (Szeged)
Befoglaló mű URL: http://acta.bibl.u-szeged.hu/55892/
Kulcsszavak: Analitikai kémia, Adszorpció
Megjegyzések: Bibliogr.: 286. p. ; összefoglalás angol nyelven
Feltöltés dátuma: 2018. dec. 06. 14:04
Utolsó módosítás: 2022. aug. 08. 15:47
URI: http://acta.bibl.u-szeged.hu/id/eprint/55983
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